Found 171 of ec50 for ALPHA-2B ADRENERGIC RECEPTORhaving polymerids = 9125,49000212,49000216,49000218,49000229,49000231,49000232 and
complexids = 50002812,50001641,50000720,50001452
Affinity DataEC50: 0.5nMAssay Description:Agonist activity at human adrenergic alpha2B receptor expressed in HEK293 cells coexpressing Gqi5 protein by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.5nMAssay Description:Agonistic activity towards human Alpha-2B adrenergic receptor was measured as ability to inhibit forskolin-stimulated synthesis of cyclic adenosine m...More data for this Ligand-Target Pair
Affinity DataEC50: 9.30nMAssay Description:Alpha-2B adrenergic receptor agonism measured as ability to inhibit forskolin-stimulated synthesis of cAMPMore data for this Ligand-Target Pair
Affinity DataEC50: 9.30nMAssay Description:Agonistic activity towards human Alpha-2B adrenergic receptor was measured as ability to inhibit forskolin-stimulated synthesis of cyclic adenosine m...More data for this Ligand-Target Pair
Affinity DataEC50: 35nMAssay Description:Agonistic activity towards human Alpha-2B adrenergic receptor was measured as ability to inhibit forskolin-stimulated synthesis of cyclic adenosine m...More data for this Ligand-Target Pair
Affinity DataEC50: 41nMAssay Description:Effective Concentration at Alpha-2B adrenergic receptor from CHO-RNG cellsMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(RAT)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataEC50: 53nMAssay Description:Agonistic activity against alpha-2 adrenergic receptor in isolated, field -simulated vas deferens from ratsMore data for this Ligand-Target Pair
Affinity DataEC50: 55nMAssay Description:Effective Concentration at Alpha-2B adrenergic receptor from CHO-RNG cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 62nMAssay Description:Agonist activity at human recombinant adrenergic alpha2B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 62nMAssay Description:Agonist activity at human alpha2B adrenoceptor expressed in CHO cells assessed as extracellular acidification by cytosensor microphysiometryMore data for this Ligand-Target Pair
Affinity DataEC50: 62nMAssay Description:Agonistic potency at human adrenergic alpha-2B receptor expressed in CHO cells assessed as forskolin-induced cAMP accumulationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: 62nMAssay Description:Agonist activity at human adrenergic alpha-2B receptor expressed in CHO cells assessed as extracellular acidification by cytosensor microphysiometryMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(RAT)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataEC50: 74nMAssay Description:Binding affinity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]prazosin as the radioligandMore data for this Ligand-Target Pair
Affinity DataEC50: 78nMAssay Description:Alpha-2B adrenergic receptor agonistic potency as inhibition of forskolin-stimulated cyclic adenosine monophosphate synthesisMore data for this Ligand-Target Pair
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Homo sapiens (Human))
National Institute Of Diabetes
Curated by ChEMBL
National Institute Of Diabetes
Curated by ChEMBL
Affinity DataEC50: 100nMAssay Description:Agonistic potency at beta-1 adrenergic receptor for the percent maximal increase in contraction rate of isolated guinea pig atriaMore data for this Ligand-Target Pair
Affinity DataEC50: 126nMAssay Description:Agonist activity at human adrenoceptor aplha 2B expressed in CHO cells assessed as rate of extracellular acidification by cytosensor microphysiometri...More data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(RAT)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataEC50: 156nMAssay Description:50% Molar effective concentration for agonistic activity against Alpha-1 adrenergic receptor in rat aortaMore data for this Ligand-Target Pair
Affinity DataEC50: 162nMAssay Description:Agonist activity at human adrenoceptor aplha 2B expressed in CHO cells assessed as rate of extracellular acidification by cytosensor microphysiometri...More data for this Ligand-Target Pair
Affinity DataEC50: 166nMAssay Description:Agonistic activity towards human Alpha-2B adrenergic receptor was measured as ability to inhibit forskolin-stimulated synthesis of cyclic adenosine m...More data for this Ligand-Target Pair
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Homo sapiens (Human))
National Institute Of Diabetes
Curated by ChEMBL
National Institute Of Diabetes
Curated by ChEMBL
Affinity DataEC50: 166nMAssay Description:Agonist activity at human brain adrenergic alpha2 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 200nMAssay Description:Agonist activity at human adrenoceptor aplha 2B expressed in CHO cells assessed as rate of extracellular acidification by cytosensor microphysiometri...More data for this Ligand-Target Pair
Affinity DataEC50: 200nMAssay Description:Agonist activity at human recombinant adrenergic alpha2B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 214nMAssay Description:Agonistic activity towards human Alpha-2B adrenergic receptor was measured as ability to inhibit forskolin-stimulated synthesis of cyclic adenosine m...More data for this Ligand-Target Pair
Affinity DataEC50: 240nMAssay Description:Agonist activity at human adrenoceptor aplha 2B expressed in CHO cells assessed as rate of extracellular acidification by cytosensor microphysiometri...More data for this Ligand-Target Pair
Affinity DataEC50: 251nMAssay Description:Agonist activity at human adrenoceptor aplha 2B expressed in CHO cells assessed as rate of extracellular acidification by cytosensor microphysiometri...More data for this Ligand-Target Pair
Affinity DataEC50: 295nMAssay Description:Agonist activity at human adrenoceptor aplha 2B expressed in CHO cells assessed as rate of extracellular acidification by cytosensor microphysiometri...More data for this Ligand-Target Pair
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Homo sapiens (Human))
National Institute Of Diabetes
Curated by ChEMBL
National Institute Of Diabetes
Curated by ChEMBL
Affinity DataEC50: 300nMAssay Description:Agonistic potency at alpha 2-Adrenergic receptor for inhibition of 10 uM forskolin-elicited stimulation of adenylate cyclase in human platelet membra...More data for this Ligand-Target Pair
Affinity DataEC50: 316nMAssay Description:Agonist activity at human adrenoceptor aplha 2B expressed in CHO cells assessed as rate of extracellular acidification by cytosensor microphysiometri...More data for this Ligand-Target Pair
Affinity DataEC50: 316nMAssay Description:Agonist activity at human adrenoceptor aplha 2B expressed in CHO cells assessed as rate of extracellular acidification by cytosensor microphysiometri...More data for this Ligand-Target Pair
Affinity DataEC50: 316nMAssay Description:Agonist activity at human alpha2B ARMore data for this Ligand-Target Pair
Affinity DataEC50: 470nMAssay Description:Effective Concentration at Alpha-2B adrenergic receptor from CHO-RNG cellsMore data for this Ligand-Target Pair
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Homo sapiens (Human))
National Institute Of Diabetes
Curated by ChEMBL
National Institute Of Diabetes
Curated by ChEMBL
Affinity DataEC50: 500nMAssay Description:Activity at alpha2 adrenergic receptor in human brain prefrontal cortex membranes assessed as effect on UK14304-induced [35S]GTPgammaS binding by mea...More data for this Ligand-Target Pair
Affinity DataEC50: 501nMAssay Description:Agonist activity at human adrenoceptor aplha 2B expressed in CHO cells assessed as rate of extracellular acidification by cytosensor microphysiometri...More data for this Ligand-Target Pair
Affinity DataEC50: 501nMAssay Description:Agonist activity at human recombinant adrenergic alpha2B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 562nMAssay Description:Alpha-2B adrenergic receptor agonism measured as ability to inhibit forskolin-stimulated synthesis of cAMPMore data for this Ligand-Target Pair
Affinity DataEC50: 646nMAssay Description:Agonist activity at human alpha2B adrenoceptor expressed in CHO cells assessed as induction of extracellular acidification by microphysiometryMore data for this Ligand-Target Pair
Affinity DataEC50: 646nMAssay Description:Agonist activity at human recombinant adrenergic alpha2B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 646nMAssay Description:Agonistic potency at human adrenergic alpha-2B receptor expressed in CHO cells assessed as forskolin-induced cAMP accumulationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: 646nMAssay Description:Agonist activity at human adrenergic alpha-2B receptor expressed in CHO cells assessed as extracellular acidification by cytosensor microphysiometryMore data for this Ligand-Target Pair
Affinity DataEC50: 692nMAssay Description:Agonistic potency at human adrenergic alpha-2B receptor expressed in CHO cells assessed as forskolin-induced cAMP accumulationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: 692nMAssay Description:Agonist activity at human alpha2B adrenoceptor expressed in CHO cells assessed as induction of extracellular acidification by microphysiometryMore data for this Ligand-Target Pair
Affinity DataEC50: 724nMAssay Description:Agonistic activity towards human Alpha-2B adrenergic receptor was measured as ability to inhibit forskolin-stimulated synthesis of cyclic adenosine m...More data for this Ligand-Target Pair
Affinity DataEC50: 776nMAssay Description:Agonist activity at human alpha2b-AR expressed in CHO cells assessed as rate of acidification after 240 mins by cytosensor microphysiometric analysisMore data for this Ligand-Target Pair
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Homo sapiens (Human))
National Institute Of Diabetes
Curated by ChEMBL
National Institute Of Diabetes
Curated by ChEMBL
Affinity DataEC50: 800nMAssay Description:Activity at alpha2 adrenergic receptor in human brain prefrontal cortex membranes assessed as effect on UK14304-induced [35S]GTPgammaS binding by mea...More data for this Ligand-Target Pair
Affinity DataEC50: 891nMAssay Description:Alpha-2B adrenergic receptor agonistic potency as inhibition of forskolin-stimulated cyclic adenosine monophosphate synthesisMore data for this Ligand-Target Pair
Affinity DataEC50: 955nMAssay Description:Agonist activity at human alpha2b-AR expressed in CHO cells assessed as rate of acidification after 240 mins by cytosensor microphysiometric analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 977nMAssay Description:Agonist activity at human alpha2B ARMore data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+3nMAssay Description:Agonistic potency at human adrenergic alpha-2B receptor expressed in CHO cells assessed as forskolin-induced cAMP accumulationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+3nMAssay Description:Agonist activity at human alpha2B adrenoceptor expressed in CHO cells assessed as extracellular acidification by cytosensor microphysiometryMore data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+3nMAssay Description:Agonist activity at human alpha2B adrenoceptor expressed in CHO cells assessed as extracellular acidification by cytosensor microphysiometryMore data for this Ligand-Target Pair
